生物测定系统/酶染色与贸易；单胺氧化酶抑制剂筛选试剂盒/100试验/EIMO-100
商品编号：
EIMO-100
品牌：
bioassaysys
市场价：
¥6180.00
美元价：
3090.00
产品分类：
酶抑制剂
公司分类：
Enzyme_Inhibitors
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
EnzyChrom™ Monoamine Oxidase Inhibitor Screening Kit
- Product Overview
- Product FAQ
- Product Citations
- Assay Service
ProtocolSDS
Application
- HTS for inhibitor screening and evaluation of monoamine oxidase inhibitors.
Key Features
- Homogeneous and convenient. "Mix-incubate-measure" type assay. No wash and reagent transfer steps are involved.
- Robust and amenable to HTS: can be readily automated on HTS liquid handling systems for processing thousands of samples per day.
Method
- FL530/585nm
Samples
- Monoamine Oxidase
Species
- All
Size
- 100 tests
Shelf Life
- 6 months
More Details
- MONOAMINE OXIDASES (MAO, EC 1.4.3.4) are a family of mitochondrial enzymes that catalyze the oxidative deamination of monoamines. Two isoforms of MAO exist, MAO-A and MAO-B, with different inhibitor selectivity and tissue distribution. MAO dysfunction is thought to be responsible for a number of neurological disorders. Unusually high or low levels of MAOs in the body have been associated with depression, schizophrenia, substance abuse, attention deficit disorder, migraines, and irregular sexual maturation. MAO inhibitors are one of the major classes of drug prescribed for the treatment of depression, Parkinson’s and Alzheimer"s diseases. BioAssay Systems MAO Inhibitor Screening Assay Kit provides a convenient fluorimetric means to screen for MAO enzyme inhibitors. In the assay, MAO reacts with p-tyramine, a substrate for both MAO-A and MAO-B, resulting in the formation of H2O2, which is determined by a fluorimetric method (λem/ex = 585/530 nm). The assay is simple, sensitive, stable and high-throughput adaptable.
Does the kit come with MAO-A and MAO-B enzymes or control MAO inhibitors?
The kit does not comes with either MAO enzyme. However, it comes with a clorgyline and pargylineas control inhibitors for MAO A and MAO B respectively.How do I store the kit?
Store kit at -20°C for long term storage.What species of MAO was the kit optimized for?
The kit was optimized for human MAO.What if I am interested in testing inhibition of a species besides human?
We recommend that you experimentally determine the Km and then adjust the volume of substrate in the Working Reagent so that the final concentration of the substrate in the 100µL Reaction Volume is near the Km.For more detailed product information and questions, please feel free to Contact Us. Or for more general information regarding our assays, please refer to our General Questions. No citations for this new product. Please check back later.You mayclick here to check if citations are available, but are not listed here yet.
If you or your labs do not have the equipment or scientists necessary to run this assay, BioAssay Systems can perform the service for you.Simply send us your samples:- Fast turnaround - Quality data - Low costPlease email or call 1-510-782-9988 x 2 to request assay service.
品牌介绍
BioAssay Systems位于加州北部，是一家专注于提供高质量试剂盒的生物技术公司，试剂盒种类广泛、使用简便、操作简单、快速且性能优越，用户不需花额外的时间来作调适测试。BioAssay Systems产品具有快速、简单、高通量（可用于HTS药物筛选）、灵敏(特别适合小鼠样品) 、准确性高和低干扰等主要特征，且采用发光、生物发光、化学发光、荧光等非放射性的检测技术，安全无害可靠。
