生物测定系统/QuantiChrom&trade；精氨酸酶抑制剂筛选试剂盒/100试验/IARG-100
商品编号：
IARG-100
品牌：
bioassaysys
市场价：
¥4380.00
美元价：
2190.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
QuantiChrom™ Arginase Inhibitor Screening Kit
- Product Overview
- Product FAQ
- Product Citations
- Assay Service
ProtocolSDS
Application
- HTS for inhibitor screening and evaluation of arginase inhibitors.
Key Features
- Safe.Non-radioactive assay.
- High-throughput. Homogenous “mix-incubate-measure” type assay. Can be readily automated on HTS liquid handling system
- Rapid and reliable. Can be completed in less than 2 hours and no 37°C heater is needed.
Method
- OD430nm
Samples
- Arginase
Species
- All
Size
- 100 tests
Shelf Life
- 12 months
More Details
- ARGINASE(L-arginine ureohydrolase EC 3.5.3.1) is present in mammals and plants. In humans, arginase is expressed predominantly in the liver, and to lesser degrees in breast, kidney, testes, salivary glands, epidermis and erythrocytes. Arginase catalyzes the conversion of arginine to ornithine and urea, important for protection against NH3 toxicity and for cell growth and repair. Excessive arginase activity has been linked to cardiovascular diseases, also contribute to vascular structural problems and neural toxicity. Studies show that arginase inhibitors have been proved to be beneficial in cardiovascular and nervous system diseases. Simple, direct and automation-ready procedures for measuring arginase inhibition are highly desirable in Research and Drug Discovery.BioAssay Systems arginase inhibitor screening kit provides a sensitive and convenient method to screen for arginase inhibitors. The method utilizes a chromogen that forms a colored complex specifically with urea produced in the arginase reaction. The intensity of the color is directly proportional to the arginase activity in the sample. Percent inhibition of a test compound can be determined by comparing the color intensity of the reaction preincubated with the test compound with the color intensity of an untreated control reaction.
Does the kit come with arginase or control inhibitors?
No, these are not included.How do I store the kit?
This kit is shipped at room temperature. Store the Arginine Buffer at -20°C, and other components at 2-8°C for long term storage.What species of arginase was the kit optimized for?
The kit was optimized for Human Arginase I.What if I am interested in testing inhibition of a species besides human?
We recommend that you experimentally determine the Km and then adjust the volume of substrate so that the final concentration of the substrate in the 250 µL Reaction Volume is near the Km.What arginase inhibitors were tested using this kit?
ABH ammonium salt.For more detailed product information and questions, please feel free to Contact Us. Or for more general information regarding our assays, please refer to our General Questions. No citations for this new product. Please check back later.You mayclick here to check if citations are available, but are not listed here yet.
If you or your labs do not have the equipment or scientists necessary to run this assay, BioAssay Systems can perform the service for you.Simply send us your samples:- Fast turnaround - Quality data - Low costPlease email or call 1-510-782-9988 x 2 to request assay service.
品牌介绍
BioAssay Systems位于加州北部，是一家专注于提供高质量试剂盒的生物技术公司，试剂盒种类广泛、使用简便、操作简单、快速且性能优越，用户不需花额外的时间来作调适测试。BioAssay Systems产品具有快速、简单、高通量（可用于HTS药物筛选）、灵敏(特别适合小鼠样品) 、准确性高和低干扰等主要特征，且采用发光、生物发光、化学发光、荧光等非放射性的检测技术，安全无害可靠。
